Study on antitumor activity of drugs and chemicals with immunomodulatory properties

  • Study of immunotropic activity of PA:
  • assessment of effect of drugs on proliferation of T- and B-lymphocytes;
  • assessment of effect of drugs on T-lymphocyte differentiation;
  • assessment of PA action on phagocytic activity of peritoneal macrophages;
  • assessment of PA influence on cellular immune response (delayed-type hypersensitivity test).
  • Assessment of specific activity of PA in the models of leukemia and solid tumors:
  • mammary adenocarcinoma,
  • colon adenocarcinoma,
  • lymphocytic leukemia,
  • melanoma.